To have the best chance of saving patients, physicians must be able to identify and characterize the microbial infection in less than an hour from the onset of sepsis.
Unfortunately, the only reliable way of identifying microbes today is through blood culturing—a 150-year-old process that takes 2 to 6 days to provide results. In the meantime, physicians tell us they are completely blind to identifying the infection for at least 48 hours.
Sepsis Survivability - Every Hour Counts
As they try to save lives, physicians need to identify infection as quickly as possible.
They know that every hour counts, but they can’t prescribe the most effective drug unless they have precise information about the infection. So they typically do the only thing they can: prescribe broad-spectrum antibiotics that are designed to fight a wide range of microbes.
If the antimicrobials aren’t effective against the specific microbe present, the patient could become another statistic. But that’s not the worst news.
Thanks to decades of over-prescription, broad-spectrum antibiotics are losing their effectiveness.
The Super Bug Crisis is Spreading Rapidly
In the fight against life-threatening microbes,
we’re falling further and further behind.
Every time a physician prescribes a broad-spectrum antibiotic that’s ineffective against a specific strain of infection, it enables the microbes to adapt. They get stronger—and with each replication as the infection grows, the number of resistant strains increases.
Over time, these strains can become totally resistant to antibiotics.
In fact, so many microbes have become drug resistant that we are quickly returning to a pre-penicillin world—a world in which physicians may regularly have to tell patients: “I’m sorry, we’ve done all we can.”
Fighting the AMR Crisis
Antibiotics in the USA
Poor antibiotic stewardship continues because there is no fast, inexpensive test that enables true stewardship.